Thursday, August 8, 2019
Is it the right decision Who has the reason The voices of the Heart or Research Paper
Is it the right decision Who has the reason The voices of the Heart or the Mind - Research Paper Example The book talks about the story of a young boy by the name of Santiago who sets out in search for treasure. Along the path that the boy chances upon, he encounters a number of people as well as feelings and emotions that he learns to inculcate within him. Finally, he realises that the riches or the ââ¬Ëtreasureââ¬â¢ that he was in search for lay in the experiences and the people that he encountered upon during the course of his journey. The boy learns to open his mind as well as his heart to a large number of things in the world and began to live life. There are a number of emotions that a man goes through during the course of his lifetime. Most of them are experienced because of the kind of company he keeps, which further help him make his decisions and understand himself better. In The Alchemist, Coelho talks about the way a man should open himself up to both his mind as well as the heart because no right decision can arrive from only one place. He writes, ââ¬Å"May love be y our guide in every part of your life.â⬠(Coelho, Paulo) Through these lines, Coelho has tried to suggest how love comes from the heart of a person, which is the truest and purest emotion that can arise. The heart is that part of a man that lets him feel and think at the same time. It helps a man to understand what going through a situation might be like. The heart is the very aspect of a man that helps him make decisions based on his feelings. When a man says, ââ¬Ëstraight from the heartââ¬â¢ then he means to say that whatever it is that he is talking about is coming from his feelings and not from his mind. The mind on the other hand is where the rational thought process of a man persists. Thus, whatever decisions a man takes from his mind, is bound to be rational and feelings and emotions are not supposed to get in the way of the same. A decision taken from the mind consists of a sense of pragmatism that removes all possibility of understanding and taking into mind the e motions of those that depend on another person. Coelho writes, ââ¬Å"At a certain point in our lives, we lose control of what's happening to us, and our lives become controlled by fate. That's the world's greatest lie.â⬠This very statement has been accounted for by the author as a notion coming from the mind of a person. It is the mind of a man that gives him reason to point wrongs and rights at everything that the individual might cross paths within during the course of his lifetime. Therefore, it is imperative for a man to be able to think with his heart and not just his mind. When we talk about the law and justice that must be given to each and everyone in society, we also must take into account their feelings. However, a man cannot go on depending upon his feelings because they might turn into negative vibes and cause havoc to the people around him. So it is important to gauge the mind of oneself and understand what lies within in order to then ask the heart for the right decision. Most people get an intuition or an inner feeling regarding a certain situation or circumstance that they might be caught up in. This feeling is the one that comes from the heart, however might not be the right thing to do sometimes. That is why it becomes vital to think straight from the mind in order to come up with the best possible
Wednesday, August 7, 2019
Anatomy and physiology, Economics Essay Example | Topics and Well Written Essays - 3000 words
Anatomy and physiology, Economics - Essay Example In this essay, the effects of cigarette smoking on the health of people and the economy of the nation will be discussed. According to the CDC, in the United States, about 19.8 percent of all individuals over 18 years of age smoke cigarettes. It has been estimated that 43.4 million people in the country resort to smoking. The activity is more in men than in women, While 22.3 percent of men smoke, only 17.4 percent of women smoke. The highest incidence of smoking is between the age groups 18- 44 years and the lowest incidence is in the age group beyond 65 years. American Indians/ Alaska Natives have the highest incidence rates of smoking amongst ethnics groups, the rate being as high as 36.4 percent. The lowest rate is seen amongst Asians (9.6 percent). In the year 2007, it was estimated that 20 percent of high school students resorted to smoking (CDC, 2009). The rates were similar in girls and boys. While 21 percent of boys were smoker, 19 percent of girls were smokers. As far as ethnic groups were concerned, 23 percent of White high school students, 12 percent of Hispanic high school children and 12 percent of African American students were smokers. Every day, approximately 2900 young people between 12- 17 years of age group resort to their first experience of smoking (CDC, 2009). Smoking is associated with many health-related problems and hence is a major health-related issue. It is a leading cause of illness and death all over the world and also in United States. It affects almost every organ of the body, causes many diseases and reduces the general health of the smoker. It has been estimated that 1 in every 5 deaths in the United States is related to cigarette smoking. Every year about 438,000 deaths occur due to cigarette smoking (CDC, 2009). According to CDC, for every single individual who dies due to cigarette smoking, 20 more people suffer from atleast one serious ill effects of smoking.
Video games are good Essay Example for Free
Video games are good Essay In this 21st generation, video games are one of the most entertaining and one of the most popular ways to enjoy time. Video games are electronic human interactive games, which can be played in different types of consoles in a variety of ways. Have you ever thought about video games being beneficial? Or not just something which helps pass time or something that is a bad addiction? Video games are so popular in todayââ¬â¢s world that, the video game business earns billions of dollars on releasing a game or a type of console. In 2010 the play station brand hit 155 million units sales of their ever so famous console, ââ¬Å"the play station 2,â⬠which is also known as the ââ¬Å"PS2. â⬠Video games are not just an entertainment but, it has turned into something much bigger, it has turned into a business and also a living for some people. Many people state that video games are bad for us, like there is a topic posted in debate. org, where people who think video games are not of any good, and surprisingly to my benefits of my opinion 67% of the people who rated the discussion disliked it! Many people also have related violent behavior to violent games, like the tragic massacre that took place on the December 12th 2012, when 20 year old Adam Lanza fatally shot 20 children and 6 adult staffs, in Sandy Hook Elementary School. Many have said that, Violent video games was one of the main motivations for Adamââ¬â¢s violent act, A TV and a radio host, named Glen beck stated that the, ââ¬Å"Sandy Hook Massacre,â⬠was caused by video games. He also states that, ââ¬Å"video games are a gateway drug for our kids and instead of a high, they get numbness, they get an indifferent heart and a mind that cannot tell the difference between fiction and reality. â⬠I strongly disagree with his point; there was violence before video games. I believe the Sandy Hook murderer was a mentally ill and an unstable teenager. If video games was the case, there are a lot of children play violent video games, like the first person shooting game ââ¬Å"Call of Duty Black Ops II,â⬠is a violent war game and the game is really realistic and it is brutal. The game went to gross $ 1 Billion in the first 15 days of availability. With so many people playing violent games there should have more than at least 50 massacres yearly according to my calculation. I mean if a normal human being plays a violent video game for maybe even more than 12 hours a week, it wont motivate or trigger us to go kill someone, you have to have some kind of a mental illness or a violent angst, to go fling around guns in public. Video games are not harmful for someone, and many parents and critics are very judgmental about it, as many kids are not properly guided and supervised while playing video games. Video games, are surely fun but an individual should be self discipline and even the parents should be able to handle and guide their children on how much they play their video games. An article by Health Central also suggests that video games are bad. It tells the readers that it makes people un-social, obese, and also it causes them to have bad grades, arenââ¬â¢t these reasons all about self-disciplinary? Are video games the main cause of this? Video Games are even in fact educational, like the game Civil-war, teaches us and gives us like a first hand experience about the American civil war fought in 1861. It also gives out facts and important dates about the civil war in the loading screen. Maybe even someone who has a hard time making friends, get along with others, while playing video games or them having the same interest in video games. ââ¬Å"A growing body of university research suggests that gaming improves creativity, perception and also decision makingâ⬠(Hotz par. 1). Experts of health central said that, video games causes people to be obese, anti-social and perform bad in schools, but I believe it is the fault of those gamers who get to addictive to video game and their lack of self-discipline. Video games cannot be blamed for those reasons. If we put it like that anything we do excessively is harm to us. Playing video games is not a bad thing at all; it instead helps us pass time more entertainingly and has benefits to it as well. A research showed that people who played video games made better decisions 25% faster than those who did not play video games. A research by University of York aimed to discover if video games improver hand-eye coordination. â⬠In order to discover this, they compared the brain activity of participants who played video games for at least 4 hours a week with the results from participants who did not play video games. The study showed that the participants who did not play video games relied mostly on a part of the brain that controls hand eye coordination. In order to complete the games, the men who were not accustomed to playing video games had to focus a large amount of mental energy on coordinating what they were seeing on the screen with the physical actions they were making on the controller. Besides hand eye co-ordination, active games like the, ââ¬Å"Nintendo Wii has promoted where you have to do things physically which has proved to improve your physicality and give you enough exerciseâ⬠(Wittman par. 5). As I mentioned before video games can be a way of living for someone nowadays, an article by Kyle Russell states that, ââ¬Å"over 60 gamers earn more than 100,000 US dollar without counting the sponsorship deals and streaming their practice games. â⬠Even I have experinced how drastically video games improve you reactions and hand eye cordination. When I was in middle school, we had to play indoor games during the winter as it used to be really cold outside to play soccer, which was really sad for me as I love soccer and I kind of didnââ¬â¢t like to play indoor game. We were made to play table-tennis, and I used to hate it as I was really not that good. Around that time was when I started playing video games and as soon as that, after two months or so, I really felt myself improving in table-tennis drastically and without practice. My reactions were really fast, I later then realized how video games had a big role in that. Video games have many benefirts, In an article by Drew Guarini posted in the Huff post says ââ¬Å"a study by a group of Italian researchers proved that video games helps dyslexic children read better. Many may still argue that, even after all these benefits video games are not worth its cost, but if we look at the long run it might save us a lot of money, a anti video game mom, Jo Ashiline also re-considered getting a video game, she said, ââ¬Å"This dilemma led me this Christmas to consider getting a video game system, at least a Wii that we could all play together. The kids pointed out that I spent $82 the last time we all went bowling, and with the Wii, we could bowl at home for free (Ashline, par. 7). Ultimately, it is apparent that video games are a lot more beneficial than many people think, video games have had its prejudices created by all the critics those have very invalid reasoning like how some said, Video games are the reason for mass massacre, or even maybe how video games causes bad-grades and obesity. Those reasons are not because of the video game, but because of lack of supervision and self-disciplinary. I think that Video games are a wonderful way to spend time while having many benefits to everyone. For the old folks who may think that video games are only for the younger one, you may want to re-consider. A study this year conducted by University of Iowa found out that, Playing brain-teasing game for just two hours a week may help slow the degree of mental decay associated with the natural aging process. (Guarini D, par. 10). Work Cited FYI: Video Game Statistics by the Entertainment Software Association. Critical Gaming Project. Word Press, n.d. Web. 18 Nov. 2013. Are Video Games Bad for Children? The Premier Online Debate Website. N. p. , n. d. Web. 18 Nov. 2013. Sandy hook shoting article Sandy Hook Shooter Motivated by Violent Video Games, Norway Massacre (Report). The Hollywood Reporter. N. p. , 18 Feb. 2013. Web. 19 Nov. 2013. Feraligatr, Caz. Glenn Beck: Video Games Are A Drug That Killed 28 People! Blog by CazFeraligatr IGN. IGN. N. p. , 22 Feb. 2013. Web. 20 Nov. 2013. Main Menu. Dependable Video Games. N. p. , 19 Sept. 2012. Web. 18 Nov. 2013. Video Gaming Increases Physical Activity. The Journal of Extension (JOE). Journal of Extension, n. d. Web. 20 Nov. 2013. Russel, Kyle. The Highest-Paid Professional Video Gamers In The World. Web log post. Business Insider. N. p. , n. d. Web. 20 Nov. 2013. Guarini, Drew. 9 Ways Video Games Can Actually Be Good For You. The Huffington Post. TheHuffingtonPost. com, 07 Nov. 2013. Web. 18 Nov. 2013. Work Cited Ashline, Jo. Video Games Were Invented by the Devil OC Moms: The Mom Blog : The Orange County Register. OC Moms: The Mom Blog. N. p. , 27 Dec. 2009. Web. 20 Nov. 2013.
Tuesday, August 6, 2019
Analysis of three sun articles on the execution of Robert Harris Essay Example for Free
Analysis of three sun articles on the execution of Robert Harris Essay These three articles printed in the sun newspaper in 1992,approach the execution of Robert Harris in very different ways . The articles have chosen to cover different parts of the Robert Harris case. Article 1 is focused on the way Robert Harris died and the T. V reporter Michael tuck giving a graphic description of the execution and the build up to it . The second article is about he nuns including Mother Teresa who tried to turn the decision around so Harriss life could be spared. Article three gives a description of where and how the victims were murdered and what how the parents felt and thought of Harriss execution. The first article explains and describes what happened to Robert Harris. It starts with a detailed description of Harriss execution. Gurgled and gasped as cyanide gas choked the life from him. This has been written as the second sentence to give an immediate impact of disgust and it plays with your emotions and it makes you more interested and you want to read on. Once the writer has got the readers attention, he then goes to the lead up to the execution. The first article is very against the death penalty as when it talks about the execution was reprieved twice before he was finally gassed, the article tries to make you feel sorry for Harris. Michael Tuck describes the execution as grisly and not a humane way to die and in this he is confirming that he is against the anti-death penalty. Alternatively, article three is not against the anti-death penalty. It starts off with Harriss victims parents, giving there opinion on Harriss execution. One of the victims farther said I have no time for do-gooders who says that he should be spared look what he did to my son. Am I supposed to erase the memory, the pain of that. This is trying to make you feel sorry for the parents of the victims and it is trying to persuade the reader that capital punishment is good. Article two is set out in a bold headline, which reads NUNS MERCY BID and under the headline is a small paragraph. It mentions Mother Teresa Name to give a sort of good feeling to the article because Mother Teresa well know personality of being warm, nice and a gentle person and it says that she appealed to a California governor Pete Wilson to spare Harriss life this sort of makes you feel that if Mother Teresa is trying to safe his life then she must be doing the right thing and Harriss life should be spared. It says in the article that there were loads of anti-death sentence campaigners who urged for the killer not to be killed. This is a fact that many people wanted Harris to live and theres evidence of Mother Teresa point of view. Theres a couple of lines in this article that say that Harris had alcoholic parents and he was fifth of nine children terrorised by there farther. His lawyers said that he may have been brain damaged by a beating at the age of two. This could make the reader feel sorry for Harris and its not fair for Harris to be killed in this way but there no evidence that the article is true. The visual presentation in the articles plays a very important role. In article one, theres a big picture above the article of two chairs where Harris was probably killed I think that this picture is trying to make you feel sorry for Harris as the picture makes you feel a sort of horrific sense of dying and displays a horrible looking setting in where people are chained to chairs and then are choked with gas and then killed. Beside the picture is TV man watches Harris in gas chamber. This is very emotive language and makes the article more dramatic. In article two there is a photo of a man I think its Harris but it could be a different number of people maybe Michael Tuck watching the execution or is it Harris himself its good as it lets the reader speculate. All three articles are made up of fact an opinion. Article one is mainly made up of opinion it is nearly all Michael Tuck telling the readers what he thought. He said But IF you ask me this is not a clean and humane way to die This is Michael Tuck expressing his opinions on the execution. Article two has got a bit of opinion He said he may have been brain damaged by a beating at the age of two The words may have means that not necessarily true. The only fact in this article is that Mother Teresa fought with other campaigners to spare Harriss life. Article three appears to be a balance of fact and opinion. The first half of the article is mainly opinion. Theres the victims parents saying what they think about Harriss execution. They were out for a fun day fishing when they were executed by this beast. It is the parents opinion that Harris is a Beast. The second half of the article seems to tell more fact, it says how the victims were killed, for the first time across the three articles. But after telling the story theres still opinions added. The grinning Harris calmly ate the boys hamburgers. There is know way that anyone could of none this so this must be opinion. In conclusion all articles have different stories, which all connect together, but as you can see Harris was an evil man as he shot two innocent boys dead for no reason at all. Language used in these articles is effective and ahs been used well to give you a clear picture of how Harris died and how he killed two innocent teenagers. People tried to save him but it didnt work. When all three articles are read separately they create a biased opinion on Harris execution, but when read together you have a balanced account of Harris case.
Monday, August 5, 2019
Kiliani-fischer Synthesis of Monosaccharides
Kiliani-fischer Synthesis of Monosaccharides Teoh Shi Hao Sean Introduction Monosaccharides are the most basic unit of carbohydrates, playing an essential role in the biochemistry of life. The most important and commonly occurring form is glucose, used as an energy source in cells (Solomon et al., 2011). Monosaccharides have the chemical formula (CH2O)n (where n 3) but those with eight or more carbons are uncommon due to their inherent instability (Solomon et al., 2011; McMurry, 2008). In a monosaccharide molecule, each carbon atom has a hydroxyl group bonded to it, except one which has an oxygen atom double bonded to it instead thus forming a carbonyl group (Solomon et al., 2011). The monosaccharide is an aldehyde if the carbonyl group is located at the end of the chain, and a ketone if the carbonyl group is located at any other position. Monosaccharides can exist in acyclic or cyclic forms, and usually switch between the two forms (McMurry, 2008). The Kiliani-Fischer synthesis is a technique for lengthening these important biomolecules. Mechanism Figure 1 below shows the reaction equation of the technique. A starting sugar is first reacted with sodium cyanide to form cyanohydrin, and subsequently hydrolysed through the application of heat to form two diastereomeric aldonic acid lactone intermediates. These intermediates are later separated through separation techniques, such as chromatography, and the desired lactone is reduced using a sodium amalgam to form a resultant sugar that has one carbon atom more than the starting sugar. In this written review, the starting sugar will be a aldopentose and the resultant sugar will be a aldohexose. Figure 1 ââ¬â Reaction equation of the Kiliani-Fischer synthesis (Kilini-Fischer synthesis, 2014; Fischer, 1890). Nucleophilic addition of aldehyde to form cyanohydrin The first step in Kiliani-Fischer synthesis involves nucleophilic addition of the starting sugar, an aldehyde. NaCN and H2O are used as reagents (McMurry, 2008). Figure 2 below shows the mechanism of the reaction. A lone pair on a CN ion initiates the reaction by attacking the nucleophilic carbon atom at the carbonyl group, forming a tetrahedral intermediate. The O then attacks the H atom of a H2O molecule, forming a cyanohydrin. Figure 2 ââ¬â Reaction of starting sugar to form cyanohydrin. Hydrolysis of cyanohydrin to form aldonic acid The second step in Kiliani-Fischer synthesis involves the hydrolysis of the cyanohydrin to form aldonic acid (McMurry, 2008). H2O is used as the reagent, with heat applied. Figure 3 below shows the mechanism of the reaction. The lone pair on the O of OH, formed by the auto-ionization of water, attacks the nucleophilic C of the cyanohydrin forming a trigonal planar structure. The lone pair on the N then attacks an H of a H2O molecule, followed by the double bond of C=N attacking the H atom bonded to the OH group. The resultant molecule is an amide. An OH ion then attacks the nucleophilic carbon at the carbonyl group, forming a tetrahedral intermediate that collapses with NH2 leaving as a leaving group. An aldonic acid molecule is formed. Figure 3 ââ¬â Hydrolysis of cyanohydrin to form aldonic acid. Esterification of aldonic acid to form lactone intermediate and subsequent reduction to form resultant sugar With the same reagent of H2O and conditions of heat, the aldonic acid produced from the hydrolysis of cyanohydrin undergoes esterification to form lactone intermediates (McMurry, 2008). Figure 4 below shows the mechanism of the reaction. A lone pair on the O at the carbonyl group of COOH attacks a proton produced by the auto-ionization of water. The tautomer of the resulting intermediate has a nucleophilic carbon, C1, which is attacked by a lone pair present on the OH group on the other end of the aldonic acid chain. The electrons from the O-H bond of the attacking OH group is withdrawn by the O+, and the resulting proton is attacked by a lone pair on the OH group attached to C1. The lone pair from the O of the other OH group attached to C1 forms a second bond between C and O, and a H2O molecule leaves as a leaving group. The electrons from the O-H bond then forms a second bond between C and O, and a proton leaves. A lactone intermediate is formed. Finally, the lactone intermediate is reduced using a sodium amalgam, Na(Hg), to form the resultant aldohexose monosaccharide (McMurry, 2008). Reagents used are sodium amalgam and sulphuric acid, in cold solution (Fischer, 1890). Figure 5 below shows the reaction equation. The exact mechanism of reduction by sodium amalgam is unknown at this point in time (Keck et al., 1994). Figure 4 ââ¬â Esterification of aldonic acid to form lactone intermediate. Figure 5 ââ¬â Reduction of aldonic acid to resultant sugar. History and development The Kiliani-Fischer synthesis is named after German chemists Heinrich Kiliani and Hermann Emil Fischer. Its original purpose was to elucidate all 16 stereoisomers of aldohexoses, as achieved by Fischer. Key discoveries that to the development of this technique included: (1) Louis Pasteurââ¬â¢s insight that the ââ¬Å"molecule of tartaric acid came in two forms that were mirror imagesâ⬠, or isomers, of one another, and that each of these isomers rotated polarized light in different directions (Wagner, 2004, p.240), (2) Jacobus H. vanââ¬â¢t Hoffââ¬â¢s and J. A. Le Belââ¬â¢s insight of the ââ¬Å"concept of an asymmetric carbon atomâ⬠, that isomers of compounds exist despite identical chemical formulae because of asymmetric carbon atoms, and the relationship between stereochemistry and optical activity (Wagner, 2004, p.240), and (3) Fischerââ¬â¢s creation of phenylhydrazine, a reagent that reacts with sugar molecules to form osazones. Prior to the discovery of this technique, relatively little was known about the structural properties of monosaccharides. It was difficult to study monosaccharides because of their ââ¬Å"tendency to form syrups rather than solids that could be dissolved and crystallized easilyâ⬠(Wagner, 2004). However, Fischer discovered phenylhydrazine which when reacted with aldonic acids (formed by oxidation of sugars) forms osazones (Kunz, 2002). These carbohydrate derivatives could be isolated easily through crystallization, and had physical forms that could be distinguished from one another (Kunz, 2002). Their subsequent analysis allowed Fischer to identify and segregate isomers of the monosaccharides (Wagner, 2004). The aldonic acid can be regenerated by addition of baryta water, or aqueous solution of barium hydroxide, to the segregated osazone (Fischer, 1890). The then purified aldonic acid can be evaporated to transform into welling-crystallizing lactone for further study (Fischer, 1 890). Using this technique, Fischer discovered that two distinct monosaccharides, D-glucose and D-mannose, yield the same osazone because osazone formation destroys the asymmetry about C2 without affecting the rest of the molecule (Wagner, 2004). Furthermore, the lactones of D-glucose and D-mannose turned polarized light in different directions. As such, he concluded that D-glucose and D-mannose have identical structures but were mirror images of one another (Wagner, 2004). However, their exact structures were still unknown. In 1886, Kiliani discovered a method to lengthen the carbon chain of an organic molecule, using cyanide as a reagent to form cyanohydrin (McMurry, 2012). Fischer realized the potential of this discovery in advancing the study of carbohydrates, adding on an additional step to convert the cyanohydrin nitrile group into an aldehyde (McMurry, 2012). Thus, the Kiliani-Fischer synthesis was created. This new technique allowed Fischer to research further into the stereoisomerism of monosaccharides and continue off where he last stopped ââ¬â that D-glucose and D-mannose were stereoisomers but of unknown structures. Applications Elucidation of aldohexose stereoisomers Figure 5 on the right shows the general structure of a aldohexose. In order to apply the Kiliani-Fischer synthesis in the elucidation of aldohexose stereoisomers, Fischer had to first make a starting assumption that the ââ¬âOH group of D-glucose at C5 was on the right side (Wagner, 2004). L-arabinose is an aldopentose having five carbon atoms. Its exact structure had been deciphered by Fischer, and is asymmetric at C2, C3 and Cà 4 as shown in Figure 6 on the right. Fischer discovered that the Kiliani-Fischer synthesis converted L-arabinose into both D-glucose and D-mannose (Wagner, 2004). This therefore implied that D-glucose and D-mannose shared the same configuration about C3, C4 and C5 as the analogous carbons in L-arabinose (C2, C3 and C4 respectively) (Wagner, 2004). This insight led Fischer to use L-arabinose in conjunction with D-glucose and D-mannose as materials for further research. Fischer discovered that oxidizing L-arabinose created a product that was optically active (Wagner, 2004). If the starting assumption made by Fischer was true, then this implied that the ââ¬âOH group at C2 in L-arabinose (and thus C3 in D-glucose and D-mannose) must be on the left side or the product would be optically inactive (Wagner, 2004). Next, Fischer determined that oxidizing D-glucose and D-mannose resulted in dicarboxylic acids that were optically active (Wagner, 2004). This implied that the ââ¬âOH group at C4 in D-glucose and D-mannose (and thus C3 in L-arabinose) must be on the right side or the product would be optically inactive (Wagner, 2004). Finally, Fischer found that oxidizing D-gulose resulted in the same dicarboxylic acid as that of D-glucose (Wagner, 2004). Through logic, Fischer realized this implied that the ââ¬âOH group at C2 in D-glucose must be on the right side. Piecing together all the information, Fischer finally determined the exact structure of D-glucose and D-mannose, as shown in Figure 7 below. Problems and improvements The Kiliani-Fischer synthesis is a commonly used technique in preparing aldoses. However, the last step in the reaction process, reduction, produces ââ¬Å"mixtures containing product aldoses, unreacted lactone, aldonic acid salts, and alditolsâ⬠(Serianni et al., 1979; p.71). Reduction by sodium amalgam allows the production of acylated aldoses in high yields but the subsequent removal of the acyl groups often degrades the product aldose (Serianni et al., 1979). An improvement to this method would be to reduce the nitrile over a palladium catalyst (Serianni et al., 1979; McMurry, 2012). This would yield an imine intermediate instead, that can be hydrolysed to an aldehyde. References Fischer, E. (1890). Synthesis in the sugar group. Journal of the American Chemical Society, 12(8), 400-409. Fischer, E. (1902). Syntheses in the purine and sugar group. Nobel Lectures, Chemistry 1901, 1921, 21-35. Keck, G. E., Savin, K. A. Weglarz, M. A. (1995). Use of samarium diiodide as an alternative to sodium/mercury amalgam in the Julia-Lythgoe Olefination. Journal of Organic Chemistry, 60(10), 3194ââ¬â3204. Kiliani-Fischer synthesis (2014). Wikipedia. Retrieved April 2, 2014 from http://en.wikipedia.org/wiki/Kiliani%E2%80%93Fischer_synthesis. Kunz, H. (2002). Emil Fischer ââ¬â unequalled classicist, master of organic chemistry, and inspired trailblazer of biological chemistry. Angewandte Chemie International Edition, 41(23), 4439-4451. Magner, J. A. (2004). Emil Fischer (1852-1919): The stereochemical nature of sugars. The Endocrinologist, 14(5), 239-244. McMurry, J. (2008). Organic Chemistry (7th edition). Belmont, CA: Thomson Brooks/Cole. McMurry, J. (2012). Organic Chemistry (8th edition). Belmont, CA: Thomson Brooks/Cole Serianni, A. S., Nunez, H. A. Barker, R. (1979). Carbon-13 enriched carbohydrates: Preparation of aldonitrile and their reduction with a palladium catalyst. Carbohydrate Research, 72, 71-78. Solomon, E. P., Berg, L. R., Martin, D. W. (2011). Biology (9th edition). Singapore, CA: Cengage Learning Asia Pte Ltd.
Sunday, August 4, 2019
Philosophy, Interdisciplinary Teaching and Student Experience Essay
Philosophy, Interdisciplinary Teaching and Student Experience ABSTRACT: This paper focuses on novel approaches open to teachers of philosophy in particular, but more generally also to other university teachers, in the face of what Allan Bloom saw as the waning of a literary culture. It is argued that, although some of Bloom's suggestions regarding the successful engagement of students' interest-against overwhelming odds-are didactically valuable, he neglects precisely those avenues from which students could benefit most on the basis of their own experience in a world largely devoid of literary attachments but saturated with audiovisual ones. These options are explored in some detail from various perspectives, including the difference between a written and an audiovisual text, the philosophical-critical potential of rock music and the interdisciplinary value of a teaching model that has student experience as its point of departure. Does the ancient discipline of philosophy still have something of value to give to university students as we approach the millenium? In a world suffused by proliferating media-images and sounds, does a discipline whose insights are born of the interpenetration of thinking and language stand any chance of being heard amid the noise, or noticed in the headlong rush for greater global investment and development? I shall argue that it does, and that philosophy is, in fact, alive (perhaps dormant) in the most unexpected practices and activities, albeit not always easy to recognize, and although philosophers and teachers of philosophy face the sometimes difficult task of enlivening these philosophical sparks into a steady flame. My argument rests on the assumption that philosophy is not only an anc... .... Being and time. Tr. Macquarrie, J. & Robinson, E. Oxford: Basil Blackwell. Kearney, R. 1988. The wake of imagination. London: Hutchinson. Kierkegaard, S. 1987. Either/or. Vol. 2.Tr. Hong, H.V. & Hong, E.H. Princeton: Princeton University Press. Lyotard, J-F. 1991. The inhuman: Reflections on time. Tr. Bennington, G. & Bowlby, R. Cambridge: Polity press. O'Neill, O. 1993. Kantian ethics. In: Singer, P.(Ed.) A companion to ethics. Oxford: Blackwell. Paglia, C. 1993. Rock as art. In: Sex, art, and American culture. London: Penguin Books. Pettit, P. 1993. Consequentialism. In: Singer, P. (Ed.) A companion to ethics. Oxford: Blackwell. Plato. 1974. Republic. Tr. Grube, G. M. A. In: Plato's Republic. Indianapolis: Hackett Publishing Co. Romney, J. 1996. Kids, a gift to middle America. In: New Statesman & Society, Vol 9, 17 May, Issue 403, p35.
Saturday, August 3, 2019
Cyber Pornography :: essays research papers fc
Geeks & Pr0n: A study of the culture behind the underground realm of cyber pornography. à à à à à The spawning of the public Internet as we know it today provided a brand new type of communication, virtually unrestricted, and naturally, as with nearly every other form of communication, has been exploited by pornography. This newly-invented category of pornography, to be called ââ¬Å"cyberporn,â⬠would not only revolutionize its own industry, but also help to speed the development and growth of the Internet. Feeding off of each other, technology and pornography have played an equally transforming role in our current methods of communication. It is important to note that in the past, communication technologies that were prevented from being used as a means of sexual communication were vastly subject to failure. For example, it is highly arguable that one of the main reasons for the victory of VHS tapes over the Beta format is that Beta refused to let pornography occupy their tapes. Similarly, many people attribute AOLââ¬â¢s victory over Prodigy to the fact that Prodigy refused to allow sexual content (Pornography and Technology). Pornography and technology are so tightly woven together that it would appear that neither can exist without the other, at least not in their current forms. Partly due to their interest in technology, it is no surprise that geeks, especially geeks of the male gender, are common consumers of the cyberporn industry. The industry is estimated to be the highest grossing sector on the Internet (Pornography and Technology), and for many geeks who spend a significant amount of time ââ¬Å"on the web,â⬠it is difficult to avoid. This paper is meant to address the culture of these geeks, and will attempt to portray to the reader the hidden lifestyle of a geek porn-addict. à à à à à This paper will not discuss the moral concerns of pornography, because though they exist, this portrayal is meant to be factual and not opinionated, and one cannot discuss morals without opinions. That said, this paper will address pornography as an addiction, and therefore a problem, when taken to certain extremities. Where these boundaries lie, however, will not be discussed; this will be left up to the reader to define. à à à à à It is difficult to define a porn-addict without laying down boundaries that have been previously forbidden, so this paper will use the simple definition of ââ¬Å"one who views pornography on a regular basis, and either suffers from or regrets his or her actions.
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