Thursday, November 28, 2019
Topic Ideas for a Reflective Essay
A List of Winning Topics for your Reflective Essay When writing a reflective essay, you have to focus on something that impressed you and made you rethink your ideas about life, relationships, faith or anything else. This might be any kind of experience: an event, trip, conversation, holiday or just an ordinary day. However, your main task is more complicated than just describing a moment of your life. You are expected to provide your personal reflection about what youââ¬â¢ve learned.As we have so many events in our life, it might be hard to recall something that can become a solid material for your writing. Read this list of reflective essay ideas to get some inspiration!Questions to ask yourself before you start writingAn essay writerà should start with answering a number of questions to get a right direction when composing a reflective essay. You can use them to develop the paragraphs of your paper and take a right angle.Why this experience was unlike any other? How did you realize this?What surprised you the most?How your e motions can be described?What situations in your life make you recall this important event? Why?Have you changed from that moment? How exactly?Can you describe your experience in a metaphoric form?Did you change your perception of this event with time? Did you make it any deeper?What questions you asked yourself after this event?Now letââ¬â¢s move to the topics. We have divided them into categories for your convenience.Significant eventsEveryday activities like cooking, walking in a park, taking a bathThe most special holiday (Birthday, Christmas, Valentineââ¬â¢s Day, etc.)Moving to another cityConcert or any other performance you took part inAn award ceremonyWhen you got your first petWhen you lost your way in an unknown cityThe most inspiring sport event you have seenThe most special date in your lifeWhen you were working on something important and your computer collapsedA dream you cannot forgetThe most unpleasant visit to a doctor youââ¬â¢ve ever hadA day, when you didn ââ¬â¢t do any of your regular responsibilitiesA situation when you defended someoneRelationshipsWhen you saw a newborn child for the first timeWhen you felt absolutely broken by the bitter truth about yourself said by someone elseA moment when you realized that you were in loveWhen someoneââ¬â¢s life inspired you to change your ownWhen you felt guilty for an unknown reasonWhen you lied and tried to hide itAn episode of your life when you felt lonelyAn episode from childhood you cannot forgetWhen you helped a person you saw for the first time (or someone you donââ¬â¢t know helped you)A moment when you felt that your family is a united bodyWhen you realized that your parents are not all-mightyWhen someoneââ¬â¢s words made you scaredSpecial placesThe street where you grew upA place where you used to hang out with friends when you were childrenA cafeteria or library where you feel calm and comfortableYour grandmaââ¬â¢s houseA vacation place your will never forgetAny other place where you had an important experience or conversationNatureWatching a sunriseWatching a sunset after a hard dayWatching a sea stormWatching on the valley from the top of a mountainWatching a flock of birds flying in the skyPicking berries and/or mushrooms in a forestBathing in a flashy streamWitnessing a natural disasterWalking/running in the heavy rainMountain climbingWalking through a place that used to be a battlefieldSeeing a wild animal in the forest
Sunday, November 24, 2019
France vs. England essays
France vs. England essays There were absolutely many differences in the way that the French and English colonized. Because England was to self-centered about their individuals than to worry anything about their colonies to the point you see France had sufficient time and occasion to colonize and try to succeed in the new world but didnt want to. Why they chose not to had to do with the political situation that arose in Europe at the time and the fact that they were lacking freedom that others had in England as well as many other causes. English colonization roared and grew and grew. Loads and loads Puritans swamped to the colonies. They saw this as an opportunity to start over and do it all their way. Because they had the freedom and right to practice and teach any religion they chose. They started over with a clean slate and a sharpie. They were not so used to this though because in England where they used to preside the British would have persecuted them if they were to do any of that. The French on the other hand didnt have this problem because the French colonies were set up not to just increase land but to make a profit. Because religious freedom was never that major of a reason that people had to move to the New French Colonies. Social conflict also factored in a huge task. People in England just were not happy and could not do anything to become happy so they all jumped on the ship and came over to the new colonies. In France there was not near as many social problems as here were in England to cause a need to be a new place to go like there needed to be in England. The colonies had very different forms of government as well. The English colonies tended to govern themselves and not be connected to England because England was worried about protecting itself. It set up grass root democracies and voting systems to kind of self govern itself and worry about its own problems. Wherea ...
Thursday, November 21, 2019
Is Political Intelligence a Powerful Form of a Leader Research Paper
Is Political Intelligence a Powerful Form of a Leader - Research Paper Example Intimidation, being a common managerial style among current business managers is gaining popularity in the corporate world. According to Kramer (2006), although subordinates find intimidating leaders rather tough and hard to deal with, these leaders, and managers find the style rather effective in managing their subordinates. Intimidation involves a number of elements, which prompts subordinates to work according to the desire of the managers. Subsequently, the managers in the organization decide on the most effective way of handling their employees. The bottom line of this researchââ¬â¢s argument; leaders have to be intimidating and equally tough in order to achieve results. However, achieving intimidation for a leader does not happen automatically in an organization. The manager has to show readiness and willingness to coarse a number of individuals in order to achieve results. How effective then is this managerial style to a manager? The fact that subordinates are responsive to its application is the main reason why the author believes ion its efficiency. Addressing managers, the author argues that the most effective method that managers can use to achieve results is the use of a political style of leadership. Without any form of compromise, a manager can get subordinates to achieve results whenever he wishes. For instance, in an organization whose subordinates show an unwillingness to handle their work, the manager can effectively use this style of management in order to achieve results.
Wednesday, November 20, 2019
Radio program about 'Conservative Muslims in Liberal Britain' Essay
Radio program about 'Conservative Muslims in Liberal Britain' - Essay Example They believe that a woman should not expose her body to the public. The conservative Muslims are keen are keen on increasing the cultural gap between them and other communities integrated in the British liberal society. They take their children specifically to Muslim schools in an effort to segregate themselves and protect their culture. The conservative Muslims donââ¬â¢t expect their children to mix with other children claiming that they may be brainwashed and persuaded to forget about their culture. The parents go to an extent of warning their children from having English or black friends. They only want the children to attend the schools where they are restricted to other humanity subjects (BBC Radio4). The Pakistani in Britain are more conservative than the ones in their home country. This is especially evident among the Muslim leaders in Britain who think they can easily be assimilated and forget about their culture. The Palestine in their home country are more liberal and outgoing. The Muslims tend to think that their children can easily adopt the Britain culture that is illegal in their religion such as gay marriages. Some of the conservative Muslims also want to maintain their cultures t hat are illegal in Britain such as polygamy. The conservative British Pakistani are so insecure around people from other races and religions. They cluster and stay in same residences away from other people. They are also less likely to marry from a different race or tribe. They believe that intermarriage will dilute their culture and customs (BBC Radio4). They also believe in confining their women in the houses or when they move out, they completely cover themselves up with the clothing. The women are not allowed to go to the mosque or work. Even those who are lucky to work they have to find jobs near home. This has deepened the differences and in the process inhibiting integration with the other people in the
Monday, November 18, 2019
Software engineering and implementation Essay Example | Topics and Well Written Essays - 5000 words
Software engineering and implementation - Essay Example It has a close relationship with a large number of other disciplines such as mathematics, physics and computer sciences (ACM, Inc., 2006). Basically, software engineering provides a wide variety of principles, practices and tools for software engineers throughout the software development process. However, the software development process is followed through a software development life cycle. In this scenario, a software development life cycle is a conceptual framework or a map, which defines the stages of a software development process. Basically, a software development life cycle divides the software development process into a number of stages. Additionally, each stage of a software development life cycle is aimed at achieving a particular objective (Rouse, 2009). Up till now, a large number of software development process models have been developed taking into consideration the objectives of a particular software. For instance, waterfall process model, spiral model, iterative models, agile models and so on. Though, each software process model is based on a specific ideology. However, the basic objective of all the software process models is to support the software development process by dividing the development effort into a number of stages. In this scenario, each software development model divides the software development process into different stages such as: requirements analysis, system design, coding, testing, implementation and maintenance. In addition, the execution of these stages depends on the requirements of a particular software (Kumar, Zadgaonkar, & Shukla, 2013). However, the execution of these stages flows in a sequence from upper to lower stage. This paper presents a detailed analysis of two most important stages of a traditional software development life cycle, these stages are: requirements analysis and software
Friday, November 15, 2019
Quantum Dots For Drug Delivery Biology Essay
Quantum Dots For Drug Delivery Biology Essay A drug delivery system can be defined as the mechanism for the introduction of drug and other therapeutic agents into the body for treating any disease. An ideal drug delivery system possesses two elements: (1) the ability to target -to ensure high efficiency and reduce the side effects, (2) controlled drug release (3) prevention of side effects [8]. Using nanomaterials for drug delivery NDD (nanoparticle drug delivery) has the following advantages: reduced drug toxicity better penetration of the particles different delivery routes minimizes the irritant reactions improved bio-availability and increased circulation time controlled drug release and targeting It is one of the Green Technology methods as the focus is on minimizing the hazard side effects and maximizing the efficiency of any chemical (drug) of choice and replacing the existing products with new nanoparticles that are friendly throughout their lifecycle[8],[7]. QUANTUM DOTS FOR NDDS: NDDS means Nanoparticle Drug Delivery System. A system with high sensitivity, large resolution, and low cost is needed for the maintenance of drug delivery i.e. to check the nanocarrier distribution, drug release and degradation inside the body. Quantum Dots are highly suitable for such systems.[1] The important characteristics of Quantum dots which make them suitable for drug delivery systems are: small size, versatility of surface chemistry to incorporate various drugs, unique optical properties for real time monitoring of drug transport and release both at systemic and cellular levels. These Quantum Dots can be used as carriers by integrating with many drugs and also used as tags for other drug carriers. [6] WHY QUANTUM DOTS One of the important reasons why Quantum Dots are preferred is that it can be used for the traceable drug delivery as it has the potential to elucidate the pharmacokinetics (what the body does to the drug) and pharmacodynamics (what the drug does to the body) of drug when it is introduced into our body [6]. Using QDs will be a combination of unique physical, chemical, and optical properties which helps to study the interactions of these nanocarriers with biological systems through real-time monitoring and calculating the biodistribution of nanoparticle, drug release, intracellular uptake and degradation [5]. Comparing to the conventional imaging techniques like MRI and PET, the optical imaging using Quantum Dots is highly sensitive with high resolution and at very cheap cost which will automatically lead to the reduction of time involved in the development of new drug and many discoveries in the field [6]. ADVANTAGES OF USING QDs Optical imaging with high resolution, high sensitivity, multiplexing, and low cost Small size which leads to less amount of drug usage and low drug toxicity Versatile surface chemistry, Improved bioavailability and delivery of drug in a controlled and sustained manner Decreased incidence of side effects and improve patient compliance Comparing other conventional probes, QDs are more resistant which allows tracking cell processes for longer periods of time and which will lead to discovery of new molecular interactions Quantum dots have size dependant emission which can be modified according to our requirement (from UV to IR range) Fluorescence is seen for longer time when compared to conventional dyes. The extremely small size gives them great flexibility by allowing them using different delivery routes eg. they can be injected as liquid mixtures, fabrics, and polymer.[7] PROPERTIES OF QDs Some of the properties of Quantum Dots that are used to examine nanocarrier behavior in biological systems are: ([2], [5],[7]) Small size: size maybe around 2-10 nm in diameter that enables tagging of drug/carriers. Single or multi-component systems can be labeled for tracing and monitoring Surface chemistry: compatibility with various drug carriers integrating a wide range of nanoparticle drug carrier system. Emission profile: identifying quantum dots by its sharp narrow emission peak allows simultaneous observation of multiple nanocarriers within a same system. High brightness: detection of QDs inside body facilitates the tracing of nanocarriers in vivo. High photostability: QDs are more resistant to photobleaching that enables long term real time tracking. QUANTUM DOTS AS NANOCARRIERS Quantum Dots are considered as carriers and the therapeutic drug molecules are directly linked to them to be delivered to the target sites. Here it serves as both vehicle carrying the drug and tracing probe used for the real time monitoring. In drug delivery, size of the Quantum Dots is considered as a very important parameter. The size of QDs varies from 2 10 nm, and it increases to 5 20 nm in diameter after drug encapsulation. It should be noted that QDs of size smaller than 5 nm are removed in the process of renal filtration and those particles bigger is size have problems in penetrating through the tissues and many bigger particles are wiped out before they could reach their destination. Another important characteristics of QDs to be considered for drug delivery is the ratio of surface-to-volume. If this ratio is high then multiple carriers can be linked on single QDs without changing the average diameter of the nanocarrier system. Thus the ratio of surface-to-volume should be high. Fig.1 A Multifunctional Quantum Dot coated with Amphiphillic Polymer [6] The above figure illustrates that QD acts as core structural hydrophobic scaffold and the amphiphillic polymer is coated outside the core. The drug molecules which are hydrophobic in nature are embedded between the core and the polymer coating. And those hydrophilic therapeutic molecules can be incorporated on the amphiphillic coating. Multiple layers of ligands can be linked in subsequent layers not directly linked to the QD core but to the previous layers of coating and is controlled by them. These nanocarriers also protect the therapeutic molecule or proteins used from the bodys own immune system defense mechanism by encapsulating them within themselves. [6] Yamomoto et al did research on using quantum dots to treat stroke in and reported that the nanocarriers QD captopril conjugates were capable of lowering blood pressure in rats. But it was not known whether the therapeutic effect of lowering pressure was due to the conjugate or the detached drug from the quantum dots. [6]. Not only drugs, other therapeutic molecules like small interfering RNA, oligodeoxynucleotide and biomolecules e.g. antibodies, peptides can also be incorporated into the nanocarriers. siRNA delivery using quantum dots was reported by Bhatia et al. siRNA moleculeas were successfully delivered using targeted nanocarriers because of the size similarity between QDs and siRNA. Whereas larger molecules like plasmid will require many QDs for successful delivery. [6] Mn-doped ZnS Qds encapsulated with glycopolypeptide were fabricated for the drug delivery. Characterization and in vitro studies were done to prove the low cytotoxicity of the nanocarriers and it was good effort for the targeted drug delivery [4]. QUANTUM DOTS AS TAGS FOR OTHER DRUG CARRIERS Due to the unique properties of Quantum Dots, they are used as tags to label other drug carriers and are used as traceable drug delivery. The high photostability helps in the real time tracking of the nanocarrier inside the body. Therefore strong fluorescence signal indicates higher uptake of drug by the cells. The wavelength of the emitted signal depends on the size of the Quntum Dots used. Thus it is very specific to the QDs and thereby simultaneous nanocarriers can be used and the signals can be easily identified. Chen et al. reported about their work of siRNA delivery with QD conjugated with Lipofectamine. The results showed that fluorescence intensity of QD is proportional to the degree of silencing i.e. if lipoplex uptake is more than the fluorescence will be stronger. [6] Another work done by Zhang et al. reported the synthesis of QD-chitosan conjugate nanobeads for the delivery of siRNA. It was successfully traced because of the conjugation with QDs. [6] Amphipol nanocpmplex were prepared for the real time imaging of siRNA by Lifeng et al. it was delivered intracellularly and imaged in a real time pattern. [12] SYNTHESIS AND CHARACTERIZATION There are many ways of preparing Quantum Dots. Some of the noted process of fabricating QDs are Lithography, Colloidal synthesis, Epitaxial methods, some chemical methods [2],[10]. Generally NDDS is prepared in the following steps: Nowadays many non-toxic semiconductor QDs are used for the drug delivery. Consider for example ZnO. It is a non-toxic semiconductor when compared to other Quantum Dots such as CdS, CdTe. These QDs can be combined with biocompatible and biodegradable polymer to increase the stability and non-immunogenicity of the nanocarriers. It also shields the nanocarriers from the interference of other interacting molecules inside biological environment. Chitosan is a natural copolymer which on encapsulation enhances the quantum dots properties like solubility in water, metal chelation and easy processing and biocompatibility [3]. Characterization studies like TEM, UV-VIS, PL spectroscopy, FTIR, Drug release response test are done after the synthesis. TEM is used to find out the size range of the fabricated QD. PL and PLE spectra give information about the emission spectra. FTIR confirms the incorporation of the drug into the QD and Drug release response test gives the amount of drug released and tells about the type of drug delivery. [10], [3]. CONCLUSION: Quantum Dots will be the future of drug delivery systems if the only drawback has been eliminated. The only disadvantage in using Quantum Dots is their long term toxicity. This can be overcome by replacing the core of the QD with biocompatible agents like gold or magnetic nanoparticles which offers a unique combination of therapy like magnetofection and photothermal treatment. Recent studies show that quantum dots to be safe on primates [9]. Quantum Dots will be a powerful tool to diagnose and treat cancer [11]. Thus quantum dots will become the new era of drug delivery.
Wednesday, November 13, 2019
Abortion Should Not be Banned :: Abortion Pro Choice Essays
The main problem in the world is inevitable abortion. Because it is about morality; which people tend pay more attention. Nowadays, Abortion is a controversial problem as people think of appropriateness. However, Abortion is necessary in many cases. Three main reasons why abortion should be banned are condition that women are not pregnancy, health problem in mother, and social problem. First, the pregnancy without readiness because the teenagers has sexual relation ââ¬Å"prematureâ⬠because nowadays it has communication is easy and comfortable. It make teenagers can getting to know it easier and sometime the women it may be deceptive in a way that is not good, for example indecent, fraudulent. Especially the pregnancy has not ready is in school because the women may be problem in social is drop out of school (Growing up global, 2005 p.540) Because of poor academic and the lack opportunities in economic not only economic but also is good occupations and social is good the children of mother have not finish it becomes problem side working, such as cheap labor in the factory. Perhaps someone is pregnant in school have an abortion in the school it help open opportunity for continue to study for the future. Sometime, husband and wife the protection of sexual relation has failed from process condom for example using low quality materials. The causes of the family i t reason why want to abortion because not ready take care a baby is born. Secondly, The health of the mother, body of physical disorders of the body. The major reason that abortion should not be banned is for preventing transmission of Human Immunodeficiency Virus (HIV) from mother to infant during pregnancy ââ¬Å"reduce maternal morbidity and mortalityâ⬠(Rudolph Gurtovnik, 2008, p.28) it is the big problem that the government has to solve and spent a lot of budget to treat all of these people. Some women feel that they have not the economic resources to take care a HIV child. A HIV status may also the cause women to reject their pregnancy. Some women need to restrict their incomes for accessing on a meditation and treatment to family membersââ¬â¢ HIV infection. On the other hands, a pregnancy woman also has a negative impact to her health HIV women access abortion because they intentionally choose not to have a child and also fear that their pregnancy would lead to both mother and child poor health and death. Finally, the main clause a big problem of social problem is the accident situation has effect when the women are raped.
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